Research Positions
Wnt/beta-catenin signaling in early breast neoplasia
Description
A postdoctoral scientist position is immediately available in the laboratory of Dr. Louise R. Howe at Weill Cornell Medical College. Dr. Howe's group uses a combination of cell biology, molecular biology and whole animal approaches to elucidate the molecular mechanisms underlying the development and growth of breast cancer (http://www.med.cornell.edu/research/lrhowe/). Our goal is to translate this basic biology into novel approaches for breast cancer prevention and treatment. Ongoing research in the lab focuses on the feasibility of preventing breast cancer through targetting the cyclooxygenase-prostaglandin signaling pathway. We are now recruiting a postdoctoral fellow for NIH-funded research into the role and regulation of Wnt/beta-catenin signaling in early breast neoplasia.
Requirements
Candidates demonstrating the ability to be highly motivated, work independently, and with a strong background in molecular and cell biology and tissue culture are encouraged to apply. Experience in cell signalling pathways would also be helpful. Candidates should have received a Ph.D. degree within the last three years. Good organizational skills are desirable, and fluent English is essential. Salary will be commensurate with experience.
Contact Information:
Please send a detailed CV including a brief summary of research experience and interests, and the names and contact details for three references to:
Louise R. Howe, Ph.D.
Department of Cell & Developmental Biology
Weill Cornell Medical College
1300 York Avenue, Box 60
New York, NY 10065
E-mail: lrhowe@med.cornell.edu
Description
Postdoctoral position available immediately to study angiogenesis in mouse models of human tumors.
The research will focus on identifying the molecular mechanisms of tumor angiogenesis, and its component processes including co-option of vascular cells from host blood vessels and recruitment of bone marrow vascular progenitor cells. The work will involve the use of existing mouse genetic models (complete deficiency of annexin 2 and related molecules), development of conditional knockouts, bone marrow transplantation, flow cytometric cell analyses and fractionation, immunohistology, functional analysis of gene-targeted endothelial cells and vascular mural cells, and genomic methods.
Requirements
Candidate should have received a PhD degree within the last three years and have documented experience in molecular biology, with special emphasis on cloning methodologies. Background in vascular development biology and mouse surgical and husbandry skills are highly desirable. Appointments are for one year, with renewal based upon satisfactory performance and funding availability.
Contact Information:
Interested candidates should send a curriculum vitae, brief summary of research interests and experience, and the names and contact information for three references to:
Dr. Katherine A. Hajjar
Department of Cell and Developmental Biology
Weill Cornell Medical College
Email: khajjar@med.cornell.edu
http://www.med.cornell.edu/research/kahajjar/
